GHK-Cu is a naturally occurring copper compound that was first discovered in human plasma. However, it has now been found in various bodily fluids like saliva and urine. This versatile compound plays many important roles in the human body.
GHK-Cu promotes the activation of wound healing, attracts immune cells, has antioxidant and anti-inflammatory effects, stimulates collagen and glycosaminoglycan synthesis in skin fibroblasts, and encourages blood vessel growth. In essence, it acts as a feedback signal that is generated after tissue injury, serving as a potent protector and anti-inflammatory agent that controls the oxidative damage. Additionally, it plays a key role in signaling tissue remodeling, which removes damaged or scarred tissue and generates new, healthy tissue.
Unfortunately, the positive effects of GHK-Cu decline with age, as its concentration in the body decreases over time.
At BionwoRx, our peptide therapy specialist, Annamarie Salyer FNP-C, can discuss your desired results and determine the right treatment plan for you. Contact us today to learn more.
Benefits of GHK-Cu.
When utilized under the care of a qualified provider, it may:
- Tightens loose skin and reverse thinning of aged skin
- Repairs protective skin barrier proteins
- Improves skin firmness, elasticity, and clarity
- Reduces fine lines, depth of wrinkles, and improve structure of aged skin
- Smooths rough skin
- Reduces photo damage, mottled hyperpigmentation, skin spots and lesions
- Improve overall skin appearance
- Stimulates wound healing
- Protects skin cells from UV radiation
- Reduces inflammation and free radical damage
- Increases hair growth and thickness; enlarges hair follicle size
How does GHK-Cu work?
Thanks to its skin-boosting powers, GHK-Cu is a popular ingredient in many anti-aging and restorative cosmetic products. This versatile molecule stimulates the production and breakdown of key skin components like collagen and glycosaminoglycans. It also regulates metalloproteinases and their inhibitors, helping to maintain a healthy skin matrix.
What’s more, GHK-Cu attracts beneficial immune and endothelial cells to sites of injury. This accelerates the wound-healing process in the skin, hair follicles, gastrointestinal tract, and even bone. In cosmetic formulas, it tightens and firms loose skin, minimizes fine lines and wrinkles, reduces sun damage and discoloration, and boosts skin cell growth for a more youthful, radiant look.
With its impressive ability to support skin structure, function, and rejuvenation, GHK-Cu is a go-to ingredient for skincare and beauty products aimed at maintaining a healthy, vibrant glow.

Facial benefits.
Copper peptide GHK-Cu is widely used in anti-aging cosmetics (INCI name: Copper tripeptide-1). Several controlled facial studies confirmed the anti-aging, firming and anti-wrinkle activity of copper peptide GHK-Cu.
- Facial cream containing GHK-Cu increases collagen in photo0aged skin, performing better than vitamin C and retinoic acid.
- GHK-Cu containing face and eye cream, improves skin laxity, clarity and appearance, reduces fine lines and the depths of wrinkles and increases skin density and thickness comparing to placebo. GHK-Cu eye cream performes better than vitamin K cream.
- GHK-Cu cream applied twice daily improves aged skin appearance, increases thickness, reduces wrinkles and strongly stimulates dermal keratinocyte proliferation. The same study found copper peptide GHK-Cu to be non-toxic and non-irritating.
Hair growth benefits.
Copper peptide GHK-Cu and its analogs strongly stimulates hair growth. The efficiency of synthetic analog of GHK-Cu was similar to that of 5% minoxidil.
Conclusion.
GHK-Cu is a versatile compound that promotes various beneficial effects. It activates wound healing, appeals to immune cells, and has antioxidant and anti-inflammatory properties. Additionally, it stimulates the production of collagen and glycosaminoglycans in skin fibroblasts, as well as the growth of blood vessels.
This safe and extensively studied compound has a wealth of positive, health-promoting effects across many tissues and systems. It has been widely used in anti-aging and cosmetic products for decades without any adverse effects, and can be easily incorporated into creams, liposomes, foams, or subcutaneous injections.
Schedule a consultation at BionwoRx today.
Do you want to find out more about GHK-Cu If so, we encourage you to schedule a consultation with Annamarie Salyer FNP-C at BionwoRx to determine if GHK-Cu is right for you.