Comparison of bright, oxygen-rich cleansed blood and darker unfiltered blood during EBO2 Ozone Therapy at BionwoRx in Carmel, Indiana

Detoxify, Rejuvenate, and Empower Your Body’s Natural Healing Systems

EBO2 Ozone Therapy at BionwoRx.

At BionwoRx: Center for Functional and Regenerative Medicine in Carmel, Indiana, we offer EBO2 Ozone Therapy, a next-generation wellness protocol designed to detoxify and revitalize your body from within. This innovative protocol combines blood filtration, ozone, oxygen, and photobiomodulation to support circulation, modulate inflammation, and promote overall vitality.

We proudly serve Carmel, Indianapolis, Zionsville, Westfield, Noblesville, and Fishers, Indiana, offering compassionate EBO2 Ozone Therapy.

This page covers:

Understanding Extracorporeal Blood Oxygenation and Ozonation

What Is EBO2 Ozone Therapy?

EBO2 (Extracorporeal Blood Oxygenation and Ozonation) is an advanced therapeutic protocol (2nd generation EBOO ozone therapy) that filters, ozonates, oxygenates, and illuminates your blood to help reduce inflammation and oxidative stress.

While traditional ozone or “10-pass” therapies only treat a small portion of your blood, EBO2 filters and treats the majority (4–6 liters) through a sophisticated device that combines ozone, oxygen, and light therapy, including UVA, UVC, red, violet, green, and infrared wavelengths.

The result is a deep-acting rejuvenation protocol that supports detoxification, improved oxygen utilization, and mitochondrial health.

Step-by-Step Overview of the Protocol

How EBO2 Ozone Therapy Works.

Step 1: Comprehensive Consultation

We begin with a consultation to review your goals, health history, and lab data to determine whether EBO2 is appropriate for you.

Step 2: Blood Filtration and Ozonation

Using two IV lines, your blood is gently removed, filtered, and treated with ozone and oxygen. The therapy also incorporates photobiomodulation, exposing the blood to specific light wavelengths to enhance mitochondrial and immune support.

Step 3: Reinfusion and Recovery

Your cleansed, oxygen-rich blood is returned to your body through the second IV line, helping remove unwanted toxins and restore cellular balance.

Step 4: Personalized Follow-Up Care

Afterwards, we provide ongoing guidance, lifestyle recommendations, and optional follow-up sessions to maintain your results.

Young woman comfortably receiving EBO2 Ozone Therapy through dual IV lines

Revitalize Your Energy, Detoxify Your Body, and Strengthen Your Immunity

Benefits of EBO2 Ozone Therapy.

  • Minimize toxins and impurities for a cleaner, healthier body.
  • Reduce systemic inflammation and promote cellular repair.
  • Boost energy, stamina, and vitality while fighting fatigue.
  • Strengthen the immune system for enhanced resilience.
  • Improve circulation and oxygenation for optimal organ function.
  • Support mitochondrial health, ATP production, and NAD⁺ balance.
  • Enhance mental clarity, focus, and metabolic performance.
  • Promote deeper, more restorative sleep and reduced brain fog.

Wellness Applications & Supportive Uses

Conditions EBO2 May Help.

EBO2 Ozone Therapy (2nd generation EBOO ozone therapy) may support individuals experiencing:

  • Chronic inflammation and fatigue
  • Autoimmune and metabolic disorders
  • Poor circulation or cardiovascular stress
  • Brain fog and low energy
  • Mold exposure and detoxification challenges
  • Post-viral or Lyme-related symptoms
  • Fibromyalgia and chronic pain
  • Heavy metals toxicity
  • Glyphosate or environmental toxin exposure

Many patients report improved energy, sleep, and mental clarity following EBO2 therapy at our Carmel clinic.

What EBO2 May Help Remove from the Blood

Substances EBO2 May Help Remove.

EBO2 Ozone Therapy (2nd generation EBOO ozone therapy) may help remove the following substances:

  • Heavy metals
  • Microplastics
  • Environmental toxins
  • Inflammatory proteins
  • Bacteria, fungi, mold, and other pathogens
  • Excess fats and cholesterol
  • Beta-2 microglobulin
  • Dead or damaged cells
  • Cellular proteins associated with chronic inflammatory processes

Schedule Your EBO2 Consultation Today.

Experience the power of oxygen, ozone, and light to restore your energy and balance from the inside out. Book your EBO2 Ozone consultation today at BionwoRx in Carmel, Indiana, and take the first step toward optimal wellness and long-term vitality.

*We require a 72 HOUR cancellation notification for this procedure. There is a $500 charge assessed for cancelling after this time frame.

Click the button below or call us today at (317) 797-9139

We will be in touch shortly to schedule your visit.

Advanced Care in a Relaxing, Supportive Setting

Why Choose BionwoRx for EBO2 Ozone Therapy.

At BionwoRx, we integrate EBO2 (2nd generation EBOO ozone therapy) into a functional and regenerative medicine framework, combining diagnostics, lifestyle optimization, and precision wellness planning.

  • Expertly Trained Clinicians — Our team has advanced training in ozone, light, and regenerative medicine.
  • State-of-the-Art Equipment — We use the latest certified EBO2 devices to ensure safety and efficacy.
  • Personalized Wellness Plans — Each therapy plan is custom-designed based on your individual health needs and goals.
  • Comfortable, Modern Environment — Our Carmel clinic offers a serene setting to make your experience calm and restorative.

Why We Love EBO2.

We frequently recommend EBO2 (2nd generation EBOO ozone therapy) as part of a personalized care plan because many patients report meaningful improvements in how they feel day to day. While individual results vary based on overall health and medical history, EBO2 stands out as a powerful supportive protocol for promoting detoxification, cellular health, and overall wellness. It is designed to complement the body’s natural healing processes and support quality of life at a foundational level.

Harnessing Oxygen, Ozone, and Light for Cellular Health

The Science Behind EBO2.

EBO2 works by oxygenating and detoxifying blood, promoting immune modulation and cellular regeneration.
The treatment can enhance mitochondrial function, supporting ATP and NAD⁺ production, key elements of energy metabolism and healthy aging.

By improving oxygen delivery and reducing oxidative burden, EBO2 may slow the aging process and restore balance throughout your body.

Expert care led by compassion and science.

At BionwoRx, your care is led by an experienced provider specializing in Functional and Regenerative Medicine. With a personalized approach that blends evidence-based science and advanced clinical insight, your treatment plan is designed around your unique health story, helping you feel better, function stronger, and live healthier.

Annamarie Salyer FNP-C

“I believe the body can heal itself when given the right support. Through Functional and Regenerative Medicine, I focus on uncovering root causes, restoring balance, and empowering patients with the tools their bodies need to repair, renew, and thrive.”

Annamarie Salyer FNP-C

Founder – BionwoRx

Real reviews.
Real healing.

Discover why our patients rave about our services in our review section. Hear their stories, read their feedback, and see why our services are making a real difference.

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D R profile picture
D R
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The micronutrient testing is an excellent test to see which vitamins and minerals you may be deficient in and the levels of each along with immune and antioxidant function data which are very important to know for optimal health . Ive also done the food sensitivity testing which is also very important to see which foods , additives and such may be adding negative issues to your daily life all ranked on timelines and levels of how sensitive you may be to each thing . The EBO2 therapy is an excellent service too for providing detoxification , blood filtering , oxygenation and such ! All of these tests and service provided at Bionworx are all great to optimize your personal health ! I highly recommend Bionworx as my whole experience there has been amazingly informative and a great learning experience too !
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Corey Miller
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I've been recommending them ever since they helped me beat Lyme disease. I struggled for over a year after having been bit with brain fog, joint pain, fatigue, and headaches. Nothing my doctor tried worked, including SOT. I reached out to BionwoRx, and Anna recommended immunotherapy, Firefly Light Therapy, EBO2, and targeted supplements. The treatment worked. I'm now Lyme-free and feel like myself again.
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Michael P profile picture
Michael P
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I can't recommend BionwoRx enough! After struggling with Lyme disease and Epstein-Barr for far too long, I finally found a functional medicine provider who truly listened and offered treatments that made a real difference. Firefly Light Therapy and EBO2 were key parts of my recovery, and nutrient therapy along with hormone replacement therapy have completely transformed my energy, overall health, and quality of life. I feel stronger, healthier, and more like myself than I have in years. Anna is incredibly knowledgeable, compassionate, and genuinely invested in helping her patients feel their best. I'm so grateful I found her and the team at BionwoRx!
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Malinda Resendez
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I had the best experience here! Great first visit and felt very welcomed! So excited for my results!!
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Ashley Dent
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Anna is theeeeee best!!!!!! She has helped me with clearing my back scars with the chemical peel service and my back is so clear and she has helped me gain my confidence back in a major way!
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Zack Henderson profile picture
Zack Henderson
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My experience with BionwoRx and Ann Marie has surpassed expectations. She is methodical and knowledgeable but more than anything she cares about the value I’m getting as a patient and even though it would be easy to upsell or drive more profit, she does the right thing. They have made me aware of the costs and treated me like a human being who is coming to them for help instead of a 5 minute window to prescribe as much high profit junk that will just keep me coming back to chase symptoms. There were health issues I was dealing with which were ruining my life and eroding my hope and Ann Marie very efficiently got me back up and running better than I thought possible. I do my research and came with a lot of questions and knowledge and instead of talking down to me from her white coat superiority, she nerded out with me. Even when there is something she can’t help with, she has taken the time to give direction and advice. This is what healthcare is supposed to be, the opposite of sick care.
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Randy Mitchell
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Can’t wait to get my first treatment Ms. Annamarie Salyer have a lot of knowledge about regenerative medicine

Our Commitment to Safe, Professional Care

Safety and Comfort at BionwoRx.

EBO2 (2nd generation EBOO ozone therapy)at BionwoRx is performed by trained clinicians using medical-grade devices and sterile protocols. The process is minimally invasive and generally well-tolerated. We screen each client for contraindications and monitor you closely throughout the procedure for maximum comfort and safety.

Other regenerative treatments.

A2M Therapy

Targets inflammation and cartilage damage at the molecular level. A2M therapy helps protect and rebuild joint tissue to relieve arthritis pain naturally.

Extracellular Vesicle (EV) Therapy

Cellular messengers that deliver regenerative signals to support healing, inflammation reduction, and anti-aging benefits.

Firefly Light Therapy™

The Firefly Light Therapy™ is a multi-spectrum LED Light Therapy for pain, neurological disorders, pathogen issues, and more.

Photobiomodulation Plasma Therapy (PPT)

A regenerative wellness procedure using a person’s own plasma with targeted light frequencies to enhance cellular function, tissue health, and recovery.

PRP Therapy (Platelet-Rich Plasma)

Harness your own platelets to stimulate repair and reduce inflammation for joint pain, tendon injuries, and hair restoration.

FAQs.

What is EBO2?

EBO2 stands for Extracorporeal Blood Oxygenation and Ozonation. It’s a modern protocol (2nd generation EBOO ozone therapy) that uses ozone, oxygen, and light to filter and rejuvenate your blood.

What is the EBO2 protocol?

Blood is gently withdrawn, filtered, and infused with ozone, oxygen, and multiple light wavelengths before being returned to your body. This process supports detoxification and improved oxygen utilization.

How often should I do EBO2?

If you are managing a significant condition, such as Lyme disease, mold exposure, EBV, vaccine reaction, or heavy metal toxicity, we recommend completing treatments once weekly for 3–4 weeks. In contrast, if you are using EB02 for general health maintenance, scheduling one treatment per quarter is ideal.

What is the main purpose of EBO2?

To help reduce inflammation, enhance oxygen efficiency, and support cellular and mitochondrial health for overall vitality.

Does EBO2 affect mitochondria?

Yes. EBO2 can positively influence mitochondrial function, ATP, and NAD⁺ production, the biochemical foundation of energy and longevity.

How is EBO2 different from regular ozone therapy or 10-pass ozone?

While traditional ozone therapy treats a small amount of blood with ozone alone, EBO2 treats most of your blood (4–6 liters) using ozone, oxygen, and photobiomodulation for deeper, systemic effects.

Is EBO2 Ozone FDA-approved?

EBO2 Ozone is an investigational regenerative wellness protocol. While we follow FDA safety guidelines, EBO2 Ozone is not FDA-approved to treat, cure, or prevent any specific medical condition.

At BionwoRx, we offer EBO2 Ozone strictly as a wellness protocol to support the body’s natural cellular function, recovery, and vitality.

Disclaimer: The services and statements described here have not been evaluated by the FDA. EBO2 is not intended to diagnose, treat, cure, or prevent any disease, and individual results may vary.

Who is not eligible for EBO2?

Patients are not eligible for EB02 if they have cancer, are pregnant or breastfeeding, take high doses of vitamin K, or have a genetic clotting disorder/

Request a personal consultation.