
Lyme disease
Your Path to Answers and Recovery Starts Here.
Lyme disease often goes undiagnosed or undertreated, leaving patients frustrated and symptomatic for years. At BionwoRx, we take a whole-body, functional medicine approach to help uncover hidden infections, reduce inflammation, and support your body’s natural healing processes.
Serving Carmel, Indianapolis, Westfield, Fishers, Zionsville and Noblesville.
This page covers:
Understanding This Complex Tick-Borne Illness
What is Lyme Disease?
Lyme disease is a tick-borne bacterial infection most commonly caused by Borrelia burgdorferi. It transmits to humans through the bite of an infected black-legged tick. While other biting insects may potentially spread Lyme disease, this idea remains controversial and requires further research to confirm.
However, Lyme is often difficult to diagnose early, and many patients develop chronic or persistent symptoms when the infection is missed or inadequately treated. Additionally, it commonly appears alongside co-infections, which further complicate recovery.
Early and Chronic Symptoms Can Vary Widely
Lyme Disease Symptoms.
Lyme affects every person differently. As a result, symptoms may appear weeks, months, or even years after infection.
Common Symptoms Include:
- Persistent fatigue
- Brain fog and memory issues
- Joint and muscle pain
- Headaches
- Sleep disturbances
- Anxiety or mood changes
- Numbness or tingling
- Heart palpitations
- Digestive issues
Furthermore, many patients never recall a tick bite or rash.

Conventional Treatment Guidelines.
In early-stage Lyme disease, conventional treatment guidelines from the Infectious Diseases Society of America generally recommend a short course of oral antibiotics, typically lasting 10 to 14 days, with longer treatment durations sometimes considered when neurological involvement is present.
While oral antibiotics may be sufficient for some early presentations, more complex or persistent cases can involve ongoing neurological, cognitive, and psychological symptoms that may require a broader treatment strategy. In our clinical experience at BionwoRx: Center for Functional and Regenerative Medicine, chronic Lyme presentations often benefit from a more comprehensive functional medicine approach that addresses immune function, pathogen burden, inflammation, and systemic recovery in addition to antimicrobial therapy.
Systemic Inflammation and Immune Dysregulation
How Lyme Disease Affects the Body.
Once inside the body, it can evade the immune system, hide in tissues, and trigger widespread inflammation. Over time, this may impact:
- The nervous system and brain
- Joints and connective tissue
- The cardiovascular system
- Digestive and detoxification pathways
- Hormones and mitochondrial function
Because of this complexity, effective care must address both the infection and the body-wide dysfunction it creates.
Advanced Functional and Infectious Disease Testing
Lyme Disease Testing at BionwoRx.
At BionwoRx: Center for Functional and Regenerative Medicine, accurate diagnosis is an important part of developing an effective Lyme disease treatment plan. Because standard Lyme testing can sometimes miss chronic or complex cases, we use advanced specialty testing methods when clinically appropriate to help identify both Lyme bacteria and associated coinfections.
Specialty Laboratory Testing for Lyme Disease and Co-infections
We may utilize advanced testing designed to detect Lyme, Co-infections, and opportunistic infections.
Advanced molecular testing may help evaluate for:
- Borrelia species associated with Lyme disease
- Babesia
- Bartonella
- Ehrlichia
- Anaplasma
- Other accompanying tick-borne pathogens that may contribute to persistent symptoms
F-Scan Frequency Assessment
We may also incorporate F-Scan (Frequency Scan), an advanced bio-resonance technology used to evaluate potential microbial imbalances and energetic stress patterns within the body.
F-Scan works by:
- Identifying the unique frequency signatures associated with pathogens
- Comparing those frequencies with known biological response patterns
- Helping detect possible microbial stressors that may contribute to chronic symptoms
This technology is used as part of a broader functional assessment to provide additional insight when evaluating complex Lyme presentations and associated co-infections.
A Personalized Functional Medicine Approach
Combination Treatments for Lyme Disease Support.
At BionwoRx: Center for Functional and Regenerative Medicine, we use a multi-system functional medicine approach for Lyme disease treatment because chronic Lyme disease and associated co-infections often require support in several areas at once. Our Combination Treatments are designed to address pathogen burden, support immune function, and help the body manage recovery through a comprehensive and individualized treatment strategy.
1. Targeted Antibiotic Therapy.
Antibiotic therapy may be used as part of a comprehensive Lyme disease protocol to help address bacterial pathogens associated with Lyme disease and related co-infections. Because these infections can present differently from person to person, treatment plans are individualized based on clinical presentation, history, and overall health needs.
Our goal is to use antibiotic strategies thoughtfully while also supporting the body during treatment, as microbial die-off and inflammatory responses can create additional physiologic stress.
2. Advanced Immunotherapy.
The immune system plays a central role in recovery from chronic Lyme disease, ongoing inflammation, and immune dysregulation. Supporting immune resilience is an important part of a functional medicine strategy designed to promote healing.
Our advanced immunotherapy protocols may include:
- Adjunctive therapies that help address immune challenges often associated with chronic Lyme disease and coinfections
- Targeted peptide therapies, including TA-1 (Thymosin Alpha-1) and BPC-157, selected to support immune modulation, gut health repair, and recovery
- Personalized supplement protocols based on individual needs, including vitamins, minerals, amino acids, antioxidants, and mitochondrial support nutrients
- Functional medicine strategies designed to help restore biological balance and support long-term wellness
3. Next-Level Detoxification and Pathogen Support.
Detoxification support is an important part of many Lyme disease treatment protocols, particularly when addressing microbial burden, inflammatory byproducts, and the physiologic stress associated with chronic infection.
At BionwoRx: Center for Functional and Regenerative Medicine, advanced therapies may include:
- EBO2 (Extracorporeal Blood Oxygenation and Ozonation) which supports pathogen reduction through blood filtration, ozonation, and photobiomodulation, while also promoting circulation, oxygen delivery, oxidative balance, and inflammation support
- Firefly Light Therapy, used as an additional supportive therapy to help address remaining pathogen burden and assist in managing associated co-infections through targeted light-based energy delivery
These therapies are integrated to support detoxification pathways, reduce biological stress, and complement broader functional medicine strategies used in Lyme disease care.
Root-Cause, Science-Driven Care
Why Choose BionwoRx for Lyme Disease Treatment.
BionwoRx stands apart because we:
- Focus on why symptoms exist, not just how to suppress them
- Use advanced functional diagnostics
- Integrate regenerative and supportive therapies
- Personalize every treatment plan
- Treat the whole person, body, brain, and immune system
Additionally, patients travel to us from Carmel, Indianapolis, Fishers, Westfield, Zionsville, and surrounding Central Indiana communities seeking answers they could not find elsewhere.
Experienced, Integrative, Patient-Focused Care
Meet Your Lyme Disease Specialist.
Your Lyme disease care team at BionwoRx brings together experience in:
Together, we work closely with you to monitor progress, adjust therapies, and support long-term recovery.

“I believe the body can heal itself when given the right support. Through Functional and Regenerative Medicine, I focus on uncovering root causes, restoring balance, and empowering patients with the tools their bodies need to repair, renew, and thrive.”
Annamarie Salyer FNP-C
Founder – BionwoRx
FAQs.
Is Lyme disease curable?
Early-stage Lyme disease often responds well to treatment. However, chronic Lyme may require a longer, integrative approach focused on immune support, detoxification, and inflammation control.
Why do Lyme tests sometimes come back negative?
Standard testing may miss chronic infections, biofilm-protected bacteria, or immune-evasive forms of Borrelia. Advanced testing often provides clearer answers.
What happens if Lyme disease goes untreated?
Untreated Lyme may lead to long-term joint pain, neurological symptoms, cardiovascular issues, and chronic fatigue.
Do I need a referral?
No referral is required to schedule a consultation at BionwoRx.



