Key takeaways
- Ozone therapy has a long-standing history — used for nearly two centuries, it treats infections, inflammation, and chronic conditions, with roots dating back to Nikola Tesla’s first U.S. ozone generator.
- Different ozone treatments vary in effectiveness — from intramuscular injections and transdermal ozone to the 10-Pass method, culminating in EBO2, the most advanced therapy combining blood filtration, ozone, oxygen, and photobiomodulation (PBM).
- EBO2 provides powerful detox and immune support — it removes toxins, fats, cholesterol, and inflammatory proteins while enhancing mitochondrial function, energy, and overall wellness, especially for patients with chronic inflammation or post-viral recovery needs.
A Brief History of Ozone Therapy and Its Modern Applications
Many people are curious about ozone therapy, and understandably skeptical. With new wellness trends emerging constantly, it’s natural to wonder whether ozone is just another fad. In fact, ozone therapy is far from new. It has a nearly 200-year history of use in medicine, helping treat infections, injuries, and chronic conditions.
Even the visionary Nikola Tesla recognized ozone’s potential. In 1896, he patented the first ozone generator in the United States, laying the groundwork for modern ozone-based treatments.
Today, ozone therapy continues to evolve. Clinics worldwide use ozone to address inflammation, chronic infections, fatigue, and neurodegenerative conditions. At BionwoRx: Center for Functional and Regenerative Medicine in Carmel, Indiana, ozone therapies, including the advanced EBO2 protocol, play a vital role in regenerative medicine and whole-body wellness.
How Ozone Therapy Works
Ozone therapy introduces ozone, a highly reactive form of oxygen, into the body. Because ozone interacts rapidly with biological tissues, it triggers a cascade of detoxification, oxygenation, and cellular repair processes. Different methods exist, but all aim to enhance cellular function, reduce inflammation, and improve overall health.
Below are four common ozone therapies, progressing from basic to advanced.
4 Common Ozone Treatments
1. Intramuscular Ozone Injections
Intramuscular injections mix ozone with a small amount of oxygen and deliver it directly into targeted muscle tissue. This approach often provides short-term relief for localized pain or acute conditions. While some patients experience temporary improvement, results are generally limited, prompting many to pursue more comprehensive therapies.
2. Transdermal Ozone (Hyperthermic Ozone Therapy)
Transdermal ozone therapy, sometimes called hyperthermic ozone therapy, combines heat with ozone exposure. Patients sit in a warm steam cabinet infused with ozone gas, allowing the skin to absorb ozone through open pores.
Although some absorption occurs, it is less efficient than intravenous methods. Multiple sessions are typically needed, and results tend to be milder.
3. 10-Pass Ozone (High-Dose Ozone Therapy)
The 10-Pass Method, also known as Lahody/Rowen Modified High-Dose Ozone Therapy, treats blood repeatedly with ozone using a vacuum technique:
- Heparinized blood is withdrawn into a sterile glass bottle
- Ozone is infused into the blood
- The ozonated blood is reinfused into the patient
- This cycle repeats up to ten times per session
Patients often report moderate rejuvenation and increased energy. However, this method does not remove fats, cholesterol, toxins, or inflammatory proteins from the blood.
4. EBO2 Therapy (Extracorporeal Blood Oxygenation and Ozonation)
The Most Advanced Ozone Therapy Available
EBO2 combines blood filtration, ozone infusion, oxygenation, and photobiomodulation (red, green, UVA, UVC, violet, and infrared light). During treatment, 4.5–7 liters of blood circulate through a high-grade filtration system that removes:
- Heavy metals
- Fats and cholesterol
- Environmental toxins
- Inflammatory proteins
- Cellular debris
Patients often notice a visible transformation: dark, oxygen-depleted blood enters the system, and clean, bright red, oxygen-rich blood returns to the body.
By directly reducing inflammation and supporting mitochondrial function, EBO2 delivers meaningful improvements in energy, recovery, detoxification, and cognitive clarity, particularly for individuals dealing with chronic inflammation, mold exposure, or post-viral syndromes.
At BionwoRx: Center for Functional and Regenerative Medicine in Carmel, Indiana, we proudly provide EBO2 and consistently observe life-changing outcomes for our patients.
Learn More About EBO2 at BionwoRx
If you want to explore how EBO2 can support detoxification, boost immunity, and enhance overall wellness, our expert team at BionwoRx: Center for Functional and Regenerative Medicine is ready to guide you.
We proudly serve patients from Carmel, Westfield, Fishers, Zionsville, Noblesville, and the greater Indianapolis area.
Important Notice
These statements have not been evaluated by the FDA. Ozone therapies, including EBO2, are investigational and are not intended to diagnose, treat, cure, or prevent any disease. As with any medical procedure, patients should consult their physician to determine whether ozone therapy is right for their health needs.
