
Lyme disease
Your Path to Answers and Recovery Starts Here.
Lyme disease often goes undiagnosed or undertreated, leaving patients frustrated and symptomatic for years. At BionwoRx, we take a whole-body, functional medicine approach to help uncover hidden infections, reduce inflammation, and support your body’s natural healing processes.
Serving Carmel, Indianapolis, Westfield, Fishers, Zionsville and Noblesville.
This page covers:
Understanding This Complex Tick-Borne Illness
What is Lyme Disease?
Lyme disease is a tick-borne bacterial infection most commonly caused by Borrelia burgdorferi. It transmits to humans through the bite of an infected black-legged tick. While other biting insects may potentially spread Lyme disease, this idea remains controversial and requires further research to confirm.
However, Lyme is often difficult to diagnose early, and many patients develop chronic or persistent symptoms when the infection is missed or inadequately treated. Additionally, it commonly appears alongside co-infections, which further complicate recovery.
Early and Chronic Symptoms Can Vary Widely
Lyme Disease Symptoms.
Lyme affects every person differently. As a result, symptoms may appear weeks, months, or even years after infection.
Common Symptoms Include:
- Persistent fatigue
- Brain fog and memory issues
- Joint and muscle pain
- Headaches
- Sleep disturbances
- Anxiety or mood changes
- Numbness or tingling
- Heart palpitations
- Digestive issues
Furthermore, many patients never recall a tick bite or rash.

Systemic Inflammation and Immune Dysregulation
How Lyme Disease Affects the Body.
Once inside the body, it can evade the immune system, hide in tissues, and trigger widespread inflammation. Over time, this may impact:
- The nervous system and brain
- Joints and connective tissue
- The cardiovascular system
- Digestive and detoxification pathways
- Hormones and mitochondrial function
Because of this complexity, effective care must address both the infection and the body-wide dysfunction it creates.
Advanced Functional and Infectious Disease Testing
Lyme Disease Testing at BionwoRx.
At BionwoRx, we use advanced laboratory testing to uncover hidden infections and immune dysfunction that conventional testing often misses.
Lyme and Co-Infection Testing May Include:
- Lyme disease antibody and antigen testing
- Tick-borne co-infection panels (Babesia, Bartonella, Ehrlichia)
- Inflammatory markers
- Immune system function
- Mitochondrial and oxidative stress markers
- Heavy metal and toxin burden
As a result, your care plan becomes precise, personalized, and targeted.
A Personalized Functional Medicine Approach
Lyme Disease Treatment at BionwoRx.
Rather than relying on medications alone, we build comprehensive treatment protocols that support:
- Immune modulation
- Detoxification pathways
- Mitochondrial and cellular energy
- Neurologic and joint health
- Hormonal balance
- Anti-inflammatory support
Each plan is customized based on your symptoms, test results, and overall health goals.
Advanced Blood Filtration, Oxygenation and Ozone Support
EBO2 Therapy for Lyme Disease.
EBO2 (Extracorporeal Blood Oxygenation and Ozonation) is one of the most advanced supportive therapies we offer for patients battling chronic Lyme disease and co-infections.
During treatment:
- Approximately 5–7 liters of blood circulate through a specialized external filtration system.
- The blood undergoes filtration, oxygenation, ozonation, and photobiomodulation with UV and red light.
- The freshly oxygenated blood then returns to the body.
EBO2 May Support:
- Reduced inflammatory burden
- Enhanced immune system activity
- Improved oxygen delivery and circulation
- Detoxification of microbial byproducts and toxins
- Mitochondrial and cellular energy production
Many Lyme patients pursue EBO2 as part of a broader integrative recovery strategy.
Root-Cause, Science-Driven Care
Why Choose BionwoRx for Lyme Disease Treatment.
BionwoRx stands apart because we:
- Focus on why symptoms exist, not just how to suppress them
- Use advanced functional diagnostics
- Integrate regenerative and supportive therapies
- Personalize every treatment plan
- Treat the whole person, body, brain, and immune system
Additionally, patients travel to us from Carmel, Indianapolis, Fishers, Westfield, Zionsville, and surrounding Central Indiana communities seeking answers they could not find elsewhere.
Experienced, Integrative, Patient-Focused Care
Meet Your Lyme Disease Specialist.
Your Lyme disease care team at BionwoRx brings together experience in:
Together, we work closely with you to monitor progress, adjust therapies, and support long-term recovery.

“I believe the body can heal itself when given the right support. Through Functional and Regenerative Medicine, I focus on uncovering root causes, restoring balance, and empowering patients with the tools their bodies need to repair, renew, and thrive.”
Annamarie Salyer FNP-C
Founder – BionwoRx
FAQs.
Is Lyme disease curable?
Early-stage Lyme disease often responds well to treatment. However, chronic Lyme may require a longer, integrative approach focused on immune support, detoxification, and inflammation control.
Why do Lyme tests sometimes come back negative?
Standard testing may miss chronic infections, biofilm-protected bacteria, or immune-evasive forms of Borrelia. Advanced testing often provides clearer answers.
Can EBO2 treat Lyme disease?
EBO2 is not a cure for Lyme disease, but many patients use it as a supportive therapy to help reduce inflammation, enhance immune activity, and support detoxification.
What happens if Lyme disease goes untreated?
Untreated Lyme may lead to long-term joint pain, neurological symptoms, cardiovascular issues, and chronic fatigue.
Do I need a referral?
No referral is required to schedule a consultation at BionwoRx.

