Discover Advanced Regenerative Healing
Why extracellular vesicle therapy is a breakthrough.
At BionwoRx: Center for Functional and Regenerative Medicine in Carmel, Indiana, we offer Extracellular Vesicle (EV) Therapy to help your body communicate, repair, and regenerate at a cellular level.
Learn what EV therapy is, how it works, the conditions it treats, and whether it’s right for you below.
Cellular Messengers for Regeneration
What are Extracellular Vesicles (EVs)?
Extracellular vesicles, or EVs, are tiny, naturally occurring particles released by your own cells. They carry important biological materials. such as growth factors, proteins, and signaling molecules, that help your body coordinate repair, regeneration, and communication between cells.
At BionwoRx, the EVs used in treatment are autologous, meaning they come from your own blood. This ensures the highest level of safety, compatibility, and effectiveness.
Extracellular Vesicle (EV) Therapy represents an advanced approach in regenerative medicine, combining the healing power of exosome therapy with platelet-rich plasma (PRP). Together, these two components work synergistically to:
- Stimulate tissue healing and regeneration
- Reduce inflammation
- Restore optimal cellular function
While exosomes are a type of extracellular vesicle, tiny messengers that enable communication between cells, our therapy enhances their benefits by pairing them with your body’s own growth factors and proteins from PRP. The result is a potent, natural treatment that helps the body heal and restore itself at the cellular level.
Why it matters.
This innovative therapy merges two of the most powerful tools in regenerative medicine:
- Exosomes (cellular messengers that stimulate healing and regulate repair)
- PRP (your body’s natural growth factors that support recovery and regeneration)
By combining these, Extracellular Vesicle Therapy offers a natural and targeted approach to healing, helping your body recover from injury, inflammation, or degeneration at the cellular level.
From Blood to Targeted Regeneration
How EV Therapy works.
Extracellular Vesicle (EV) Therapy is designed to activate and support your body’s natural healing processes using your own biologic materials. The procedure is quick, minimally invasive, and performed right in our clinic.
- Step 1: Blood Collection and Preparation: A small sample of your blood is drawn and processed in a centrifuge to separate platelet-rich plasma (PRP), the portion rich in growth factors, cytokines, and other healing components.
- Step 2: Concentrating the Healing Messengers: During this process, your blood also releases extracellular vesicles, including exosomes, which are collected and prepared for reinfusion. These microscopic particles carry molecular “instructions” that help coordinate repair and regeneration throughout the body.
- Step 3: Targeted Reintroduction: The final blend—rich in both PRP and extracellular vesicles—is then carefully reintroduced into the body, either through injection or infusion. Once delivered, the vesicles act as cellular messengers, guiding healing, reducing inflammation, and supporting optimal cell function in the targeted tissues.
- Step 4: Healing and Regeneration: Over the following days and weeks, these regenerative signals continue to encourage tissue repair, improved circulation, and balanced cellular communication, helping the body restore function from the inside out.
Applications for Pain, Aging, and Wellness
Conditions treated with EV therapy.
PRP therapy is used to support healing in many chronic and age-related conditions, including:
- Osteoarthritis and joint pain (knees, shoulders, elbows, wrist, foot, ankle)
- Tendon and ligament injuries
- Muscle tears and sports injuries
- Hair thinning and hair loss
- Skin rejuvenation and scar reduction
- Sexual dysfunction (Erectile Dysfunction, Vaginal Atrophy)
- Chronic inflammation and post-surgical recovery
Comprehensive Regenerative Solutions
Our EV therapy services.
At BionwoRx, our PRP services are designed to target key areas of health and wellness:
- Joint Injections: Support cartilage repair, reduce inflammation, and restore mobility naturally.
- Hair Restoration: Stimulate dormant follicles and promote hair growth.
- Skin Health: Enhance skin tone, elasticity, and reduce fine lines, wrinkles, and scars.
- Sexual Wellness: Improve sensitivity, performance, and overall reproductive health with targeted EV therapy.
- Additional Uses: Post-surgical healing, chronic pain support, immune modulation, and overall tissue regeneration.
Ready to experience the healing power of EV Therapy?
Experience advanced regenerative medicine with Extracellular Vesicle Therapy at BionwoRx. Contact us today to schedule a personalized consultation in Carmel, Indiana, and explore the benefits of cellular-level healing.
Click the button below or call us today at (317) 797-9139
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Why Patients Choose EV Therapy
Benefits and Conditions That May Improve with Extracellular Vesicle Therapy.
Because Extracellular Vesicle (EV) Therapy works by enhancing communication and repair between cells, its potential benefits reach across multiple body systems. Patients often report improved energy, reduced inflammation, and faster recovery following treatment.
At BionwoRx: Center for Functional and Regenerative Medicine in Carmel, Indiana, we use EV Therapy to help the body repair and restore function naturally, whether from chronic conditions, injury, or the effects of aging.
Potential benefits include:
- Reduced inflammation and pain
- Enhanced cellular repair and regeneration
- Improved immune and mitochondrial function
- Better circulation and oxygen delivery to tissues
- Faster post-surgical or injury recovery
- Increased energy and vitality
- Improved brain and nerve function
Conditions That May Benefit from EV Therapy:
Extracellular Vesicle Therapy may support patients experiencing:
- Joint pain and arthritis
- Neurological and neurodegenerative conditions (including Parkinson’s, Alzheimer’s, and neuropathy)
- Autoimmune and inflammatory conditions (such as lupus, rheumatoid arthritis, and IBS)
- Long COVID and chronic fatigue syndromes
- Hormonal imbalance and metabolic dysfunction
- Post-surgical or trauma recovery
- Skin and tissue rejuvenation
- Immune and mitochondrial dysfunction
- Chronic infections and stealth pathogens (Lyme disease, Epstein-Barr virus, etc.)
A natural path toward regeneration
By combining the regenerative potential of exosomes and platelet-rich plasma (PRP), EV Therapy offers a natural, non-pharmaceutical way to help your body heal and perform at its best, from the cellular level up.
Meet Your EV Therapy Specialist.
At BionwoRx, your care is led by an experienced provider specializing in Functional and Regenerative Medicine. With a personalized approach that blends evidence-based science and advanced clinical insight, your treatment plan is designed around your unique health story, helping you feel better, function stronger, and live healthier.
“I believe the body can heal itself when given the right support. Through Functional and Regenerative Medicine, I focus on uncovering root causes, restoring balance, and empowering patients with the tools their bodies need to repair, renew, and thrive.”
Annamarie Salyer FNP-C
Founder – BionwoRx
EV Therapy is Safe and Minimally Invasive
Safety, Risks, and Recovery.
- Autologous therapy minimizes risk of immune reaction
- Mild swelling or soreness may occur at the injection site
- Performed in a sterile, clinical environment
- Individual responses vary; your provider will develop a personalized treatment plan
Scientific Support for EV Therapy
Research & Clinical Evidence.
Kordelas et al., 2014 – MSC-derived EVs in Graft vs Host Disease
Zhang et al., 2020 – EVs for osteoarthritis and cartilage repair
Wang et al., 2022 – EVs in skin regeneration and wound healing
EV therapy is an emerging regenerative field with growing evidence for joint repair, tissue regeneration, hair restoration, skin rejuvenation, and functional wellness.
FAQs.
What are extracellular vesicles and exosomes?
Extracellular vesicles (EVs) are tiny, naturally occurring particles released by your body’s cells. They carry proteins, lipids, and genetic material that allow cells to communicate and coordinate healing and repair. Exosomes are a specific type of extracellular vesicle, essentially the body’s microscopic “messengers,” that play a key role in regulating inflammation, regeneration, and immune balance.
Who is a good candidate for EV or exosome therapy?
Anyone seeking to improve healing, reduce inflammation, enhance energy, or support healthy aging may be a candidate. It’s especially beneficial for those with chronic conditions or those recovering from injury or surgery.
Is EV therapy FDA-approved?
While extracellular vesicle and exosome therapies are not yet FDA-approved for specific conditions, they are being actively researched in regenerative medicine and used safely in clinical settings for their potential to promote healing and reduce inflammation.
Can EV therapy be combined with other treatments?
Yes. EV therapy can complement other Functional and Regenerative Medicine treatments such as PRP, plasma photobiomodulation, and IV nutrient therapy for enhanced results.
Are EV therapies painful?
Most patients experience only mild discomfort; topical numbing or local anesthesia can be used for added comfort.
Are EV therapies covered by insurance?
Generally considered elective; financing options are available.