Man running on the beach at sunrise, representing vitality and peak performance supported by BionwoRx’s Health Optimization Program in Carmel, Indiana.

Maximize Vitality, Resilience, and Longevity

Bion Core™

At BionwoRx: Center for Functional and Regenerative Medicine in Carmel, Indiana, we offer Bion Core™ a data-driven Health Optimization program that combines advanced functional testing, precision interventions, and regenerative therapies.

Bion Core™ redefines proactive health: instead of waiting for illness, we optimize performance at the cellular level. We use precision diagnostics and personalized care to address root causes and deliver measurable improvements.

We proudly serve Carmel, Indianapolis, Zionsville, Westfield, Noblesville, and Fishers, Indiana, offering compassionate Heath Optimization.

This page covers:

A Proactive, Science-driven Approach

What is Health Optimization?

Health optimization means actively enhancing how your body functions today and protecting that function for tomorrow. Rather than reacting to disease, Bion Core™ identifies hidden barriers at the cellular, hormonal, metabolic, and genetic levels, and corrects them using evidence-based, personalized interventions.

Our Philosophy

We treat you as a partner in care. With deep diagnostics, iterative plans, and ongoing support, we aim to create durable improvements in energy, cognition, resilience, and biological age.

A Four-stage, Data-driven Process

How Health Optimization Works.

  1. Baseline Deep-Diveadvanced labs, genetics, imaging and movement screens establish objective baselines.
  2. Precision Plan — BionwoRx provider synthesizes data into a prioritized roadmap (nutrition, hormones, detox, sleep, movement).
  3. Implementation and Therapies — combine in-clinic modalities (PBM, EBO2, regenerative injections), prescriptions, and lifestyle changes.
  4. Measure and Iterate — track biomarkers and outcomes, refine interventions, and scale to maintenance.

Functional Testing Support

Program Areas of Focus.

We address the full spectrum of health drivers. Below are the program pillars and the testing we use to personalize each plan.

Cellular Function

Restore energy at its source

  • Assess mitochondrial health, ATP production, and oxidative stress.
  • Interventions: mitochondrial support, targeted nutrition, PBM (photobiomodulation), PPT, and EBO2 when indicated.

Genetic Testing (Gene Mutations)

Know your blueprint

  • Identify clinically relevant gene variants (methylation, detox, lipid metabolism).
  • Use genotype-informed recommendations for nutrition, supplementation, and medication choices.

Diet and Nutrition

Fuel for function

  • Personalized dietary recommendations based on metabolic phenotype and goals.
  • Testing: comprehensive nutrition analysis, micronutrient profiles, organic acids testing.

Gut Health

Optimize digestion and immunity

  • Test: gut microbiome analysis, SIBO testing, leaky gut evaluation, Candida testing, fungal antibodies.
  • Interventions: targeted probiotics, prebiotics, peptide therapy, elimination plans, and gut-restorative protocols.

Food Sensitivities / Allergies

Remove invisible triggers

Inflammation

Turn down systemic fire

  • Testing: CRP, cytokines, oxidative stress markers.
  • Interventions: anti-inflammatory nutrition, targeted supplementation, PBM, EBO2, and detox support.

Detoxification

Support natural clearance pathways

  • Testing: liver panel, phase II detox markers, heavy metals, environmental pollutants.
  • Interventions: guided detox protocols, binders, nutritional support, and genetic-informed detox plans.

Stealth Infections

Uncover hidden drains on your health

  • Testing: Lyme and tick-borne panels, EBV and viral reactivation screens, other chronic pathogen testing.
  • Interventions: targeted antimicrobial/antiviral strategies, herbal therapy, immune support, EBO2, and detoxification.

Hormones

Balance energy, mood, and metabolism

  • Comprehensive Hormone Testing: female hormone panel, male hormone panel, thyroid panel (TSH, T3, T4, Free T3/4), cortisol and adrenal health.
  • Interventions: bioidentical hormone optimization, adrenal protocols, and thyroid management.

Sleep Management

Fix the foundation of recovery

  • Assess sleep architecture, circadian health, and breathing patterns.
  • Interventions: sleep hygiene, chronobiology strategies, targeted nutrient therapies, and referrals for diagnostic sleep testing when indicated.

Stress Management

Improve resilience and recovery

  • Tests and metrics: cortisol and HRV (heart rate variability) when helpful.
  • Interventions: breathwork, HRV biofeedback, psychotherapy referrals, and adaptogenic support.

Biological Age

Track and slow aging

  • Tools: telomere testing, biological-age panels, and metabolic biomarkers.
  • Goal: reduce biological age markers with personalized interventions.

Exercise

Move better, last longer

  • Functional movement and performance evaluation.
  • Recommendations: strength, conditioning, mobility, and sport-specific recommendations with recovery optimization.

Musculoskeletal

Restore function and ease pain

  • Assessment: biomechanics, joint health, movement screening.
  • Interventions: PBM/Class IV laser, peptide therapy and regenerative injections.

Functional Testing Included (detailed).

Every area above is supported by high-resolution, evidence-based testing:

Comprehensive Hormone Testing

  • Female hormone panel (estradiol, progesterone, testosterone, DHEA, SHBG)
  • Male hormone panel (total/free testosterone, DHT, estradiol, DHEA)
  • Thyroid function: TSH, T4, Free T4, T3, Free T3, reverse T3
  • Cortisol and adrenal health (diurnal saliva or serum profiles)

Advanced Gut Health and Digestion Testing

  • Food allergy and sensitivity testing
  • Gut microbiome analysis (bacterial, viral, fungal)
  • Fungal antibodies and Candida testing
  • Leaky gut (intestinal permeability) evaluation
  • SIBO breath testing
  • Gut parasites testing

Nutrition and Micronutrient Testing

  • Comprehensive nutrition analysis
  • Micronutrient panels (vitamins, minerals, antioxidants)
  • Organic acids testing for metabolic and mitochondrial status

Detoxification and Genetic Testing

  • Liver panel and detox markers
  • Methylation testing (key SNPs)
  • Telomere testing (biological age)
  • Environmental pollutants and heavy metals testing

Blood Sugar and Metabolic Health

  • Fasting glucose, Hemoglobin A1C
  • Insulin resistance assessment (HOMA-IR, insulin levels)

Anemia and Oxygenation

  • CBC, ferritin, iron studies, B12, folate

Inflammation and Immune Testing

  • CRP, ESR, cytokines, oxidative stress panels, autoimmune screens

Fatigue and Stress Testing

  • Adrenal stress tests, comprehensive baseline labs

Infectious Disease Testing

  • Lyme and tick-borne panels, EBV, and other chronic infection screens

Preventative and Annual Testing

  • Annual fasting labs: CBC, CMP, lipid panel, A1C, TSH, ferritin
  • Optional age follow-up

What Patients Commonly Achieve

Benefits of Health Optimization.

  • Increased daily energy and cognitive clarity
  • Better sleep and faster recovery from exercise or illness
  • Improved body composition and metabolic health
  • Reduced chronic inflammation and symptom burden
  • Enhanced immunity and fewer sick days
  • Slowed biological aging markers and improved longevity metrics

Who Benefits Most

Conditions Health Optimization May Help.

  • Chronic fatigue, brain fog, and low energy
  • Hormone imbalances
  • Metabolic dysfunction (pre-diabetes, insulin resistance)
  • Digestive disorders, SIBO, and food sensitivities
  • Post-infectious syndromes (Lyme, EBV, long-haul)
  • Autoimmune and chronic inflammatory conditions
  • Athletes seeking performance gains and faster recovery

Our Edge in Functional and Regenerative care

Why Choose BionwoRx for Bion Core™.

  • Integrated model: We combine functional medicine diagnostics with regenerative therapies (PBM, EBO2, targeted injections).
  • Advanced testing: We use high-resolution labs and genetics others may not offer.
  • Personalized care: Plans align with your genes, labs, goals, and lifestyle.
  • Long-term support: Follow-ups, and escalation pathways keep you on track.
  • Regional access: Serving Carmel, Indianapolis, Zionsville, Westfield, Fishers, Noblesville, and Central Indiana.

Expert care led by compassion and science.

At BionwoRx, your care is led by an experienced provider specializing in Functional and Regenerative Medicine. With a personalized approach that blends evidence-based science and advanced clinical insight, your treatment plan is designed around your unique health story, helping you feel better, function stronger, and live healthier.

Annamarie Salyer FNP-C

“I believe the body can heal itself when given the right support. Through Functional and Regenerative Medicine, I focus on uncovering root causes, restoring balance, and empowering patients with the tools their bodies need to repair, renew, and thrive.”

Annamarie Salyer FNP-C

Founder – BionwoRx

Real stories.

Real healing.

Discover why our patients rave about our services in our review section. Hear their stories, read their feedback, and see why our services are making a real difference.

Safety through Oversight and Data

Is Health Optimization Safe?

Health optimization is safe when grounded in clinical oversight. At BionwoRx we:

  • Conduct thorough baseline screening and informed consent
  • Use guideline-based dosing for supplements and hormones
  • Monitor labs regularly and adjust interventions promptly
  • Prioritize non-invasive first-line treatments and escalate safely when needed

Evidence-based Plus Precision Innovation

Research and Clinical Evidence.

Many components of Bion Core™ (nutrition, sleep, exercise, hormone optimization) have robust clinical evidence. Emerging areas, mitochondrial therapies, microbiome modulation, and precision genomics show promising results. We apply peer-reviewed science to individual care and document outcomes to continually refine protocols.

FAQs.

What does Bion Core™ cost?

Costs vary by testing, therapies, and program intensity. We offer tiered packages and financing. Contact our team for a personalized estimate.

How fast will I see results?

Some changes (sleep, energy) can appear within weeks. More complex areas (mitochondrial health, biological age) often require months. Results vary.

Do you prescribe hormones?

Yes, we prescribe and monitor bioidentical hormone therapy when clinically indicated as part of a personalized plan.

Do you take insurance?

Some labs may be covered. Many optimization services are elective.

Is genetic testing required?

No. Genetic testing enhances personalization but is optional. We design effective plans with or without genetics.

Can I choose only one module (e.g., gut health)?

Absolutely. You can start with targeted modules and scale into the full Bion Core™ program when ready.

Request a personal consultation.